OraQuick ADVANCE® Rapid HIV-1/2 Antibody Test
OraQuick ADVANCE Rapid HIV-1/2 Antibody Test

Detection is the first step in prevention. Stop the spread of HIV one simple test at a time.

The OraQuick ADVANCE® Rapid HIV-1/2 Antibody Test detects antibodies to HIV-1 and HIV-2 in 20 minutes.


  • Rapid
    Provides results in 20 minutes, enabling patients to learn their status in a single visit and allows HIV positive patients to be connected to care immediately.
  • Flexible
    Approved for oral fluid, plasma, fingerstick or venipuncture whole blood specimens. Ideal for both clinical and non-clinical settings.
  • Accurate
    Greater than 99% agreement with confirmatory Western blot.1
  • Simple
    CLIA-waived for oral fluid, fingerstick and venipuncture whole blood and offers the ability to test in non-traditional testing environments, such as outreach programs and mobile testing clinics.
  • Patient-Preferred2
    Offers patients accurate HIV testing without the need for blood or needles. Pain-free testing with oral fluid means more people get screened, more HIV positive patients are connected to care and fewer people are exposed.

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The current CDC guidelines urge routine HIV screening3

The Facts

  • More than 1.1 million people in the U.S. are infected with HIV and the CDC estimates that one in six don’t know it.4,5
  • These uninformed people cause 54-70% of the 56,300 new infections annually.6
  • 75% of HIV+ people will change risky behaviors when they learn their status.7

Risk-based testing is NOT reaching the goal of identifying all HIV+ people. The CDC guidelines recommend taking these steps to help stop the spread of HIV


  • Screen all people 13-64 years old in all healthcare settings.
  • Identify all HIV+ people. Connect them to care early.
  • Educate people about risk factors to empower them to stay healthy.

Online Ordering available for OraQuick ADVANCE® Rapid HIV 1/2


Flexible Specimens for Clinical and Non-Clinical Settings

Simple Testing Procedure

Oral Fluid (CLIA-waived)

Patient-preferred.2 Ideal for outreach programs and paraprofessionals.

*Please note the test must be used in conjunction with CDC guidelines for HIV testing and the communication and confirmation of reactive test results. Please see step-by-step instructions or package insert for complete directions.

Step 1 - Collect
sample.

Step 1 - Collect sample

Swab between the teeth and
upper and lower gum once.

Step 2 - Insert the device
into the buffer.

Step 2 - Insert the device into the buffer

Step 3 - Read between 20
and 40 minutes.

OraQuick

Non-Reactive
Line in the C Zone

OraQuick

Preliminary Positive
Line in the C and T Zones

Simple Testing Procedure

Fingerstick (CLIA-waived)

*Please note the test must be used in conjunction with CDC guidelines for HIV testing and the communication and confirmation of reactive test results. Please see step-by-step instructions or package insert for complete directions.

Step 1 - Collect
sample.

Step 1 - Collect sample

Step 1b - Mix sample
in buffer.

Step 1b - Mix sample

Step 2 - Insert the device
into the buffer.

Step 2 - Insert the device into the buffer

Step 3 - Read between 20
and 40 minutes.

OraQuick

Non-Reactive
Line in the C Zone

OraQuick

Preliminary Positive
Line in the C and T Zones

Simple Testing Procedure

Venipuncture Whole Blood (CLIA-waived)

*Please note the test must be used in conjunction with CDC guidelines for HIV testing and the communication and confirmation of reactive test results. Please see step-by-step instructions or package insert for complete directions.

Step 1 - Collect
sample.

Step 1 - Collect sample

Step 1b - Mix sample
in buffer.

Step 1b - Mix sample

Step 2 - Insert the device
into the buffer.

Step 2 - Insert the device into the buffer

Step 3 - Read between 20
and 40 minutes.

OraQuick

Non-Reactive
Line in the C Zone

OraQuick

Preliminary Positive
Line in the C and T Zones

Simple Testing Procedure

Plasma (Moderately Complex)

*Please note the test must be used in conjunction with CDC guidelines for HIV testing and the communication and confirmation of reactive test results. Please see step-by-step instructions or package insert for complete directions.

Step 1 - Collect
sample.

Step 1 - Collect sample

Step 1b - Mix sample
in buffer.

Step 1b - Mix sample

Step 2 - Insert the device
into the buffer.

Step 2 - Insert the device into the buffer

Step 3 - Read between 20
and 40 minutes.

OraQuick

Non-Reactive
Line in the C Zone

OraQuick

Preliminary Positive
Line in the C and T Zones

  1. OraQuick ADVANCE® Rapid HIV-1/2 Antibody Test Package Insert.
  2. GMHC 2008 HPLS Presentation.
  3. Revised Recommendations for HIV Testing of Adults, Adolescents, and Pregnant Women in Health-Care Settings, MMWR, September 22, 2006/Vol. 55/No. RR-14.
  4. Campsmith M et al, MMWR, October 2008.
  5. Estimates of New HIV Infection in the United States, CDC HIV/AIDS Facts, August 2008.
  6. CDC, B. Branson, HIV Testing:2005 Update presentation, June 6, 2005.
  7. Group Intervention to Reduce HIV Transmission Risk Behavior Among Persons Living with HIV/AIDS, S.C. Kalichman,Behavior Modification, March 2005.

The information provided on this website is intended only for the residents of the United States. The products discussed herein may have different labeling in different countries and may not be for sale in all other countries.

Page last updated: January 21, 2013